A Case of Hantavirus Pulmonary Syndrome.

Lee, Kye Young; Kim, Yun Seup; Jee, Young Koo; Bai, Hyun Ju; Yun, Sung Cheul; Kim, Keun Youl

doi:1997.44.6.1382

Tuberc Respir Dis > Volume 44(6); 1997 > Article

Case Report

Tuberculosis and Respiratory Diseases 1997;44(6):1382-1389.
DOI: https://doi.org/10.4046/trd.1997.44.6.1382 Published online December 1, 1997.

A Case of Hantavirus Pulmonary Syndrome.

Kye Young Lee, Yun Seup Kim, Young Koo Jee, Hyun Ju Bai, Sung Cheul Yun, Keun Youl Kim

Department of Internal Medicine, College of Medicine Dan Kook University, Chunan, Korea.

Abstract

Hantavirus pulmonary syndrome(HPS) is a systemic disease that is caused by a newly discorved and characterized virus of the Hantavirus genus, which is most frequently referred to as the sin nombre virus. The clinical syndrome resembles other hantavirus syndromes worldwide, except that it is characterized by a brief prodromal illness followed by rapidly progressive, noncardiogenic edema, and that it is more deadly than any previously recognized hantavirus infection. The clinical manifestations of HPS are characterized by four clinical phases prodrome, pulmonary edema and shock, diuresis, and convalescence. Mortality is greatest in the first 24 hours of the pulmonary edema and shock phase of the illness. These phases are strikingly similar to the clinical phases of Hemorrhagic fever with renal syndrome(HFRS) induced by Hantaan virus, except that HPS has not been associated with renal failure and Disseminated intravascular coagulation(DIC). We here report a case of hantavirus pulmonary syndrome developed in a 58 year-old man. He had a flu-like illness followed by the rapid onset of respiratory failure due to noncardiogenic pulmonary edema. HPS was diagnosed by clinical manifestations, identification of high titer antibody to Hantaan virus antigen and histologic finding of transbronchial lung biopsy (TBLB) specimen. The patient was treated with mechanical ventilation and initial corticosteroid pulse therapy resulting in successful outcome.

Key Words: Hantavirus Pulmonary Syndrome(HPS), Noncardiogenic pulmonary edema

TOOLS

PDF Links
Full text via DOI
Download Citation
Share :

METRICS

1 Crossref
Scopus
2,268 View
12 Download

Related articles

A Case of Pulmonary Coccidioidomycosis1990 December;37(4)

A Case of Pulmonary Nocardiosis1990 June;37(2)

A Case of Primary Synchronous Lung Cancer1989 December;36(4)

Clinical Observations of the Solitary Pulmonary nodules1989 December;36(4)

A Case of Caplan`s Syndrome with Pulmonary Tuberculosis1989 September;36(3)

ABOUT

ARTICLE & TOPICS

Article category

Browse all articles >

Topics

Browse all articles >

BROWSE ARTICLES

FOR CONTRIBUTORS

Editorial Office: 101-605, 58, Banpo-daero, Seocho-gu (Seocho-dong, Seocho Art-Xi), Seoul 06652, Korea
Tel: +82-2-575-3825, +82-2-576-5347 Fax: +82-2-572-6683 E-mail: katrdsubmit@lungkorea.org