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Tuberc Respir Dis > Volume 66(1); 2009 > Article
Tuberculosis and Respiratory Diseases 2009;66(1):27-32.
DOI: https://doi.org/10.4046/trd.2009.66.1.27    Published online January 1, 2009.
Clinical Characteristics and Prognosis of Lung Cancer Patients Admitted to the Medical Intensive Care Unit at a University Hospital.
Kyoung Min Moon, , Min Soo Han, , Sung Kyu Lee, , Ho Seok Jeon, , Yang Deok Lee, , Yongseon Cho, , Dong Jib Na,
Department of Internal Medicine, Eulji University School of Medicine, Daejeon, Korea. hms43@eulji.ac.kr
Abstract
BACKGROUND
The management of patients with lung cancer has improved recently, and many of them will require admission to the medical intensive care unit (MICU). The aim of this study was to examine the clinical characteristics and to identify risk factors for mortality in patients with lung cancer admitted to the MICU. METHODS: We conducted retrospective analysis on 88 patients with lung cancer admitted to the MICU between April 2004 and March 2008. RESULTS: Of the 88 patients (mean age, 66 years), 71 patients (80.7%) had non-small cell lung cancer and 17 patients (19.3%) had small cell lung cancer. Distant metastasis were present in 79 patients (89.8%). The main reasons for MICU admission were acute respiratory failure (77.3%), sepsis (11.4%), and central nervous system dysfunction (4.5%). Mechanical ventilation was used in 54 patients (61.4%). Acute Physiology and Chronic Health Evaluation (APACHE) II score, length of MICU stay, need for mechanical ventilation, source of MICU admission were correlated with MICU mortality. The type of lung cancer and metastasis were not predictive factors of death in MICU. CONCLUSION: Most common reason for ICU admission was acute respiratory failure. Mortality rate of lung cancer patients admitted to the MICU was 65.9%. APACHE II score, length of ICU stay, need for mechanical ventilation, source of MICU admission were predicted factors of death in the MICU.
Key Words: Lung cancer, Intensive care unit, APACHE II score, Mechanical ventilation


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