| Site of Bronchodilatation with Inhaled Fenoterol and Ipratropium Bromide in Bronchial Asthma |
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Chun Soo Oh, In Seon Choi, Chang Hoon Song, Young Chul Kim, Jung Il Kim, Jae Beom Yang, Kyung Ok Park |
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Department of Internal Medicine, Chonnam University Medical School, Chonnam, Korea |
| 기관지천식에 있어서 흡입성 Fenoterol과 Ipratropium Bromide에 의한 기도확장부위에 관한 연구 |
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오춘수, 최인선, 송창훈, 김영철, 김정일, 양재범, 박경옥 |
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| Abstract |
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To assess site of action of bronchodilatation with a beta adrenergic agonist, fenoterol, and an anticholinergic bronchodilator, ipratropium bromide, we measured the density dependence of maximal expiratory flow rate in 37 asthmatics There were no significant changes in Δ V max 50 with either agent. However, there were significant inverse correlations between the prebronchodilator Δ V max 50 and the change in ΔV max 50 after the administration of fenoterol or ipratropium.
These results suggest that sites of bronchodilatation in asthmatics are not different between fenoterol and ipratropium, and those are related to the prebronchodilator site of obstruction. |
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