A case of SIADH with Pulmonary Tuberculosis and Tuberculous Meningitis

Park, Chong Jin; Paik, Nam Jong; Lee, O Jung; Park, Sung Hak; Byun, Hae Won

doi:1978.25.1.22

Tuberc Respir Dis > Volume 25(1); 1978 > Article

Case report

Tuberculosis and Respiratory Diseases 1978;25(1):22-25.
DOI: https://doi.org/10.4046/trd.1978.25.1.22 Published online March 1, 1978.

A case of SIADH with Pulmonary Tuberculosis and Tuberculous Meningitis

Chong Jin Park, Nam Jong Paik, O Jung Lee, Sung Hak Park, Hae Won Byun

Deptment of Internal Medicine, Catholic Medical College, Seoul, Korea

폐결핵 및 결핵성 뇌막염과 동반된 SIADH 1예

박중진, 백남종, 이오정, 박성학, 변해원

Abstract

It was well known that the syndrome of inapproprate secretion of antdiuretic hormone (SIADH) has been associated with many pulmonary diseases, cancers, diseases of the central nervous system, and drugs. But there were a few reports of the SIADH associated with pulmonary tuberculosis and tuberculous meningitis in spite of its high prevalence rate in Korea. We experienced a case of the SIADH associated with pulmonary tuberculoss with tuberculous meningitis. Before the start of therapy, his serum sodium concentration was 127 mEq/L, serum osmolality 265 mOsm/Kg., urinary sodium concentration 310 mEq/day, and the urine osmolality 590mOsm/Kg. The creatinine clearance and intravenous insulin tolerance test for adrenal reserve function was normal. No other causes of this SlADH were apparent. Neverthless, the most probable underlying cause of SIADH in this case was pulmonary tuberculosis combined with tuberculous meningitis. This was fully recovered after combined antituberculous therapy.