On Resistant Strains of Tuberculosis Bacilli among Ambulatory Tuberculosis Patients

Lee, Sang Jun

doi:1957.0.4.47

Tuberc Respir Dis > Issue 4; 1957 > Article

Tuberculosis and Respiratory Diseases 1957;4:47-50.
DOI: https://doi.org/10.4046/trd.1957.4.1.47 Published online December 1, 1957.

On Resistant Strains of Tuberculosis Bacilli among Ambulatory Tuberculosis Patients

Sang Jun Lee

Department of Bacteriology, Kyung Buk University, Medical College, Korea

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이상준

Abstract

Modern methods of chemotherapy in treating tuberculosis have achievd remarkable tremendous results in recent years, but the appearance of tubercle bacilli resistant to the various chemical agents has cast a dark shadow on the treatment of the disease. Many studies have already been reported on this subject and this requires serious attention and profound interest in the treatment of the tuberculosis patient. The author made a comprehensive study of the resistant tubercule bacilli by stain method in 702 cases during the period of October 1955 to August 1956 at the T. B.Center, Taegu Medical College Hospital. to evaluate the percentage of positive stain cases and positive culture cases as the appearence of resistant strains of tubercule bacilli to the chemical agents.
Conclusion
1) Among the 275 cases of positive culture patients. 161 cases (58.5%) were resistant to Streptomycin, 49 cases (17. 9%) to PAS, and 23 cases (8.4%) to INAH. 2) Among the patients who have not been treated with the anti-tuberculosis chemical agents. 5 cases (7%) were found to be resistant to Streptomycin. and only 1 case (5%) was found to be resistant to PAS. 3) The resistance of tuberculose bacilli to the anti-tuberculosis chemical agents was proportionately stronger as the dosage of the agents employed become greater.