| Vanishing Lung |
|
Hun Ki Min |
|
College of Medicine, Seoul National University |
| Vanishing Lung의 일례 |
|
민헌기 |
|
|
|
|
| Abstract |
|
The phenomenon of “ vanishing lung", descriptive of the occurerance of abnormal air spaces in the process of pulmonary disease, has greatelý increased in its incidences in recent years under the effect of chemotherapy.
The following case is an example of "Vanishing lung" observed in tuberculosis during chemotherapy.
Report of a case
The patient was a 33-years-old soldier, who was in a past of active duty during the war. Diagnosis of pulmonary tuberculosis was first made by army doctor about 3 years ago. He receivd chemotherapy from September, 1954, with PAS and ST. And on that occasion, tuberculous bacilli was said positive in sputum by smear. ln December, 1954, he was hospitalized in our clinic and physical examination revealed diffuse moist rale audibleat any pal t of the lung and marked clubbed fingers. Tuberculous bacilli was negative in sputum and E. S. R was normal. Raentogenogram showed, as seen in Fig. I. A, extensive. rather soft lesion in Ieft upper field of Iung and generally severe marking in both Iungs. He was given INAH 400 mg and PAS 10g daily.
Subsequently. though there was some improvement of general condition, moderate degree of dyapnea was persist ing. ln February 1955, for the purpose of inhibiting fibrosis, cortisone was tried with daily dose of 50mg, total amount being 500mg. but this was not so effective.
in April 1955, the second ranentogenog ram(Fig 1. B) showed that the previous lesion was completely replaced by large air space. Tuberculous baciIIi was also negative in sputum both by smear and culture.
In tuberculosis, confluent extensive processes as a rule result either in thick waIIed cavities or in dense fibrosis. Now, in this case, it is considered that chemotherapy. especiaIly the effect of IN AH, and partly the effect of cotisone brought about complete resolution of pathologicaJ product3 before any of these changes could occur.
Another current trend to explain “ vanishing Iung" is as a phenomenon of obstructive emphysema. But it is said that there is neither clinical evidence of bronchiaI obstruction before its development nor evidence for such obstruction in subsequent morphological changes. |
|
PDF Links
Full text via DOI
Download Citation
