A case of rhabdomyosarcoma arising at the pleura.

Lee, Jin Goo; Choi, Kyung Mook; Shin, Sang Won; In, Kwang Ho; Kang, Kyung Ho; Kim, Joon Seok; Yoo, Se Hwa; Won, Nam Hee; Lee, Yoon Seok

doi:1993.40.3.308

Tuberc Respir Dis > Volume 40(3); 1993 > Article

Original Article

Tuberculosis and Respiratory Diseases 1993;40(3):308-313.
DOI: https://doi.org/10.4046/trd.1993.40.3.308 Published online June 1, 1993.

A case of rhabdomyosarcoma arising at the pleura.

Jin Goo Lee¹, Kyung Mook Choi¹, Sang Won Shin¹, Kwang Ho In¹, Kyung Ho Kang¹, Joon Seok Kim¹, Se Hwa Yoo¹, Nam Hee Won², Yoon Seok Lee³

¹Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea
²Department of Pathology, College of Medicine, Korea University, Seoul, Korea
³Department of Internal Medicine, Chunggoo General Hospital, Seoul, Korea

Abstract

Although uncommon, rhabdomyosarcomas are one of the most frequent forms of cancer of soft parts, particularly in children under the age of 15. There has been only one case of primary rhabdomyosarcoma arising at the pleura, reported by Hamada, Japan, 1989, in the world. A case of primary rhabdomyosarcoma arising at the pleura is reported This 15-year-old male patient was admitted to the hospital due to a one-month history of dyspnea on exertion and massive right pleural effusion. Pleural biopsy revealed embryonal rhabdomyosarcoma histologically. Immunohistochemical study shows positive reactivity to desmin, vimentin, and cytokeratin. Ultrastructural demonstration of thin and thick myofilaments was most helpful for confirming the histopathological diagnosis. The patient was received 6 cycles of chemotherapy with adriamycin, cyclophosphamide, vincristine and dacarbazine. The chemotherapy response was fairly good that the patient’s symptom was absent and pleural effusion and mass size was improved 6 months after chemotherapy This paper reports the second case of primary rhabdomyosarcoma of the pleura in the world with the review of literature.

Key Words: Rhabdomyosarcoma, Pleura, Chemotheherapy