| A clinical study of pulmonary hamartoma. |
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Sung Eun Kim1, Hong Lyeol Lee1, Se Kyu Kim1, Joon Chang1, Chul Min Ahn1, Sung Kyu Kim1, Won Young Lee1, Kyu Ok Choe2, Kyung Young Chung3, Dong Hwan Shin4 |
1Department of Internal Medicine, Yonsei University School of Medicine, Seoul, Korea
2Department of Diagnostic Radiology, Yonsei University College of Medicine, Seoul, Korea
3Department of Thoracic & Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea
4Department of Pathology, Yonsei University College of Medicine, Seoul, Korea |
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| Abstract |
Background
Pulmonary hamartomas are benign tumors that occur in the parenchyma or in the bronchi. They present as a solitary pulmonary nodule(SPN) or as a cause of bronchial obstruction The incidence, once minimal, is increasing in Korea. To get clinical spectrum about the tumor, we analyzed all the reported cases in Korea since 1964.
Methods
We reviewed the clinical, radiological and pathologica l findings of 13 patients of intrapulmonary or endobronchial hamartomas in Severance Hospital and of 38 reported cases in Korea published in literature from 1964 to 1992 retrospectively.
Results
Including 17 endobronchial hamartomas, 54 cases were studied. There were 25 men and 29 women, with a mean age of 47. 2 yea rs; 45.3 years in endobronchial type and 51. 3 years in parenchymal type. Pulmonary symptoms were present in 8 patients (22%) of intra pulmonary type and in all patients of endobronchial type: cough (65%), dyspnea (53% ), sputum (35%), fever (29% ) in order. On chest X-rays, a telectasis was seen in 10 patients (59%) in endobronchi a l type; but SPN was noted in 36 patients (97% ) of intrapulmonary type. Calcification was present in 7 intapulmonary hamartomas (23%); but is in 2 endobronchial hamartomas (12%). The diagnostic yield was 6 out of 14 (43%) in endobronchial ones; 4 out of 7 (57%) in intrapulmonary ones. Fifty pa ti ents under went operati ons as follows: lobectomy (28), enucleation (8), resecti on (8), bilobectomy (4), pneumonectomy (2). The hamartomas were 1. 2 times more common in the right lung; mean tra nsverse diameter at the time of operation was 2. 3 cm in endobronchial type, 3. 8 cm in intra pulmonar y ones. Chondroid components were present in 11 (65%) of 17 endobronchial ones but in 30 (91 %) of 33 intrapulmonary hama rtomas. No malignant changes were seen perioperative period and up to early 1993
Conclusion
The younger age in endobronchial hamartomas, the preponderance of the female sex and the more incidence in the right lung, and t he diagnostic choice of lobectomies were different from the studies of the Western countries. |
| Key Words:
lntrapulmonary Hamartoma, Endobronchial Hamartoma |
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