| Clinical studies about diagnostic yields according to variable diagnostic methods in lung cancer. |
|
Dae Song Kang, Jin Ung Cho, Sang Gyun Kim, Mi Ae Kim, Sung Uk Yang, Tae Quan Lee, Tae Hun Lee, Kwi Wan Kim |
|
Department of Internal Medicine, Presbyterian Medical Center, Chonju, Korea |
|
|
| Abstract |
Background
Lung cancer has become one of the most common cancers in Korea. lt is important to determine the accurate histologic types and stages because of different therapeutic modality. especially in small cell carcinoma. This study was designed to evaluate diagnostic yields according to variable diagnostic methods in lung cancer.
Methods
The records of 683 patients with a confirmed diagnosis of primary lung cancer during the period of 7 years. from January, 1986 until December, 1992 at Presbyterian Medical Center were analyzed retrospectively.
Results
1) Age and sex distributions Male: female sex ratio was 5.57 : 1 and age distributions were 7th decade 41.4%. 6th decade 30.2%. 8th decade 17.0% . 5th decade 7.9%. 4th decade 2.5%. 9th decade 1.3% . and 3rd decade 0.2% in decreasing order.
2) The frequencies according to histologic cell types were squamous cell carcinoma 44.7%. small cell carcinoma 23.9%. adenoca rcinoma 22.8%, alveolar cell carcinoma 2.5%. large cell carcinoma 1.2%. mixed fonns 1.2%. undifferentiated cell carcinoma 0.6% and malignant fibrous histiocytoma O.2%(1 case) in decreasing order.
3) The most common locations of lung cancer were in left upper lobe and right lower lobe, a nd no differences of diagnostic methods according to locations were noted.
4) ln central lesions. bronchoscopic examination was very accurate and frequently used diagnostic method. and in peripheral lesions, transthoracic lung biopsy (TTLB) was apparently accurate method.
5) The diagnostic yields of bronchoscopic biopsy. bronchial brushing, sputum cytology, transthoracic Iung biopsy and transbronchial lung biopsy (TBLB) were 81.3%.57.5%.31.1 %. 69.6% and 61.6%, respectively.
6) The concordance rates between the histologic diagnosis with bronchial brushing and sputum-cytology， were 91.3% and 98.4%. respectively.
7) lt was appropriate in lung cancer to repeat sputum cytology 3 to 5 times.
Conclusion
Bronchoscopic examination is important to determine the histologic cell types in lung cancer. ln addition. we should be interested in improving diagnostic yields of sputum cytology as an easy method. |
| Key Words:
Lung cancer, Bronchoscopy, Diagnostic method, Diagnostic yield |
|
PDF Links
Full text via DOI
Download Citation
