A case of Pulmonary Veno-occlusive Disease.

Cho, Jae Youn; Lee, Sang Youb; Lee, Sang Hwa; Suh, Jeong Kyung; Shim, Jae Jeong; In, Kwang Ho; Kang, Kyung Ho; Yoo, Se Hwa; Kim, Kwang Taek

doi:1996.43.2.274

Tuberc Respir Dis > Volume 43(2); 1996 > Article

Case Report

Tuberculosis and Respiratory Diseases 1996;43(2):274-279.
DOI: https://doi.org/10.4046/trd.1996.43.2.274 Published online April 1, 1996.

A case of Pulmonary Veno-occlusive Disease.

Jae Youn Cho, Sang Youb Lee, Sang Hwa Lee, Jeong Kyung Suh, Jae Jeong Shim, Kwang Ho In, Kyung Ho Kang, Se Hwa Yoo, Kwang Taek Kim

¹Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
²Department of Chest Surgery, Korea University College of Medicine, Seoul, Korea.

Abstract

Pulmonary veno-occlusive disease is a rare cause of pulmonary hypertension in which the primary abnormality is obliterative obstruction of pulmonary veins, especially venules. Clinicaly, we should suspect this disease in the case of congestive cardiac failure with pulmonary hypertension, chronic interstitial pulmonary edema, and normal or elevated wedge pressure on cardiac catheterization. We experience a case of pulmonary hypertension due to pulmonary veno-occlusive disease. A 55-years -old woman developed progressive dry cough and dyspnea for 3 months. Physical examination showed normal heart sounds, diffuse crackles in the whole lung fields. The liver was not palpable and pitting edema was absent. The diagnosis was made by chest HRCT, 2-D echocardiography, normal pulmonary capillary wedge pressure on cardiac catheterization, and confirmed by thoracoscopic lung biopsy. This patient was treated with vasodilator(calcium antagonist) and with mild symptomatic improvement. We reported a case of pulmonary veno-occlusive disease with review of literatures.

Key Words: Pulmonary hypertension, Pulmonary veno-occlusive disease