A Study of Pathological and Bacteriological Examination for the Specimens of Pulmonary Tuberculous Lesions of Resected Lung

Kim, J. S.

doi:1957.0.4.1

Tuberc Respir Dis > Issue 4; 1957 > Article

Tuberculosis and Respiratory Diseases 1957;4:1-46.
DOI: https://doi.org/10.4046/trd.1957.4.1.1 Published online December 1, 1957.

A Study of Pathological and Bacteriological Examination for the Specimens of Pulmonary Tuberculous Lesions of Resected Lung

J. S. Kim

36th Army Hospital Masan

절제폐결핵병소의 병리조직학적 연구 -특히 화학요법과 병변의 성상급조직내세균소견의 관련

김진식

Abstract

“Study of pathologic and bacteriological investigation for the specimens of pulmonary tuberculous lesions of the 100 cases of resected lung was performed at the thoracic surgery section in the 36th Army Hospital Masan, Korea, in order to reach some conclusions concerning the relationship of the histological change of tuberculous lesions and distribution of the T B bacilli in histological specimens to chemotherapy. The following conclusions were drawn. (1) By the chemotherapy the following resulted. a) cleansing in cavitary lesions. b) incleasing of collagenous encapsulation in caseous lesions. c) decreasing of caseation, tubercle formation and central necrosis of tubercles in exudative lesions. d) increasing of fibrosis d tubercles and catarrhal pneumonic changes in perifocal area. (2) By chemotherapy. 27% of cavity revealed the cleansing of cavity (disappearance of speciific reaction for TB), especially in one case a epithelization of èavity wall was observed. (3) best results were shown at 6 months chemotherapy for all tuberculous lesioions, with atrophy in epithelioid cells and disappearance in giant cells, however, the fad that specific tissue reaction appeared again after 13 months chemotherapy might be due to the close relation with the occurance of bacilli tolerance for anti-tuberculous drugs. (4) The synchysis of caseous lesions was soon in 55%, especially with a high percentage in those caseous lesions combined with cavitary lesions. A re-destruction of encapsulated caseous lesions was shown in many cases of tuberculoma and in this case, it seemηd that a opening of drnining bronchi to lesions and the infiltration of polymerphnucleaous leucocytes at the conjunction of draining bronchi would be played the important role. (5) ln the reaction ‘of chemotherapy. a ) poor-effectiveness for tuberculoma .b) good effectiveness for non- cavitary. caseous lesions at 3 months chemotherapy.

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