| A Case of Nonclassifiable Interstitial Pneumonia after Allogeneic Hematopoietic Stem Cell Transplantation . |
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Ki Hwan Jung, Hwa Jung Sung, Ju Han Lee, Joungho Han, Chol Shin, Hyung Joo Park, Je Hyeong Kim |
1Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea. chepraxis@korea.ac.kr
2Department of Pathology, Korea University Ansan Hospital, Ansan, Korea.
3Department of Pathology, Saumsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
4Department of Thoracic and Cardiovascular Surgery, Korea University Ansan Hospital, Ansan, Korea. |
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| Abstract |
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Despite the improvements in supportive care, early and late hematopoietic stem cell transplantation-related complications still remain a significant cause of morbidity and mortality. Pulmonary complications occur in 40~60% of patients who undergo allogeneic hematopoietic stem cell transplantation. Late-onset noninfectious pulmonary complications can occur months and even years after transplantation. Interstital lung disease has also been reported to be a late post-transplant complication. Exposure to cytotoxic drugs and/or irradiation has been implicated as a cause of pulmonary toxicity including pulmonary fibrosis. We report a case of an 18-year-old female with non-classifiable interstitial pneumonia that manifested eight and a half years after allogeneic hematopoietic stem cell transplantation. The condition worsened rapidly and the patient eventually died. |
| Key Words:
Hematopoietic stem cell transplantation, Interstitial lung disease, Pneumothorax |
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