A Case of Papillary Adenocarcinoma Presenting with Multiple Cysts.

Chon, Suyeon; Kim, Yu Jin; Kyung, Sun Young; An, Chang Hyeok; Lee, Sang Pyo; Park, Jeong Woong; Jeong, Sung Hwan; Cho, Eun Kyung; Sung, Yon Mi; Kim, Na Rae

doi:2010.68.2.93

Tuberc Respir Dis > Volume 68(2); 2010 > Article

Case Report

Tuberculosis and Respiratory Diseases 2010;68(2):93-96.
DOI: https://doi.org/10.4046/trd.2010.68.2.93 Published online February 1, 2010.

A Case of Papillary Adenocarcinoma Presenting with Multiple Cysts.

Suyeon Chon, Yu Jin Kim, Sun Young Kyung, Chang Hyeok An, Sang Pyo Lee, Jeong Woong Park, Sung Hwan Jeong, Eun Kyung Cho, Yon Mi Sung, Na Rae Kim

¹Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea. light@gilhospital.com
²Department of Radiology, Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea.
³Department of Pathology, Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea.

Abstract

A 23-year old woman was admitted to our hospital with hemoptysis. The chest X-ray showed reticulonodular opacity and multiple cysts throughout the entire lung field. The chest CT scan revealed numerous bilateral cysts with various sizes, some of them with thickened walls. An open lung wedge resection was performed. The resected specimen showed scattered small nodules, 0.3 to 0.6 cm in size. Microscopically, each nodule was composed of atypical glands with an occasional papillary architecture spreading to the alveolar septa, which were morphologically consistent with a papillary adenocarcinoma with a bronchioloalveolar carcinoma growth pattern. Immunochemically, the tumor cells were negative for the S-100 protein. The patient was diagnosed with an adenocarcinoma of the lung. A variety of diseases can produce or mimic multiple, thin-walled cysts in the lung. Lung cancer with multiple cysts is quite rare. Nevertheless, adenocarcinoma should be a diagnostic consideration. We report a case of a multiple cystic adenocarcinoma of the lung.

Key Words: Lung Neoplasms, Adenocarcinoma, Cysts