A Case of Pulmonary Sarcoidosis with Elevated Carcinoembryonic Antigen (CEA).

Yang, Mi Yean; Ryu, Yang Seon; Ko, Hee Ja; Park, Se Kyng; Park, Jong Sook; Park, Chun Sik; Park, Jae Sung; Bak, Sang Hyen; Ko, Eun Suk; Park, Jeong Mi

doi:2010.69.1.48

Tuberc Respir Dis > Volume 69(1); 2010 > Article

Case Report

Tuberculosis and Respiratory Diseases 2010;69(1):48-51.
DOI: https://doi.org/10.4046/trd.2010.69.1.48 Published online July 1, 2010.

A Case of Pulmonary Sarcoidosis with Elevated Carcinoembryonic Antigen (CEA).

Mi Yean Yang, Yang Seon Ryu, Hee Ja Ko, Se Kyng Park, Jong Sook Park, Chun Sik Park, Jae Sung Park, Sang Hyen Bak, Eun Suk Ko, Jeong Mi Park

¹Division of Pulmonology & Allergy, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea. schalr@schbc.ac.kr
²Department of Radiology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
³Department of Pathology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
⁴Department of Nuclear Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.

Abstract

Sarcoidosis is a multi-systemic granulomatous disorder of unknown etiology. The characteristic pathological finding is the presence of non-caseating granulomas. The lungs are primarily affected, however other organs may be involved causing various symptoms and ambiguous laboratory findings can be present. There are a few reported cases of sarcoidosis with elevated tumor markers. We describe a 68-year-old woman presenting with sarcoidosis showing elevated serum carcinoembryonic antigen (CEA). The possibility of cancer arising from serum CEA such as gastrointestinal cancer, breast cancer and lung cancer was excluded. A transbronchial lung biopsy demonstrated a non-caseating granuloma without necrosis. As a result prescribed 30 mg prednisolone daily to the patient and serum CEA was decreased after 1 month of treatment. We report a case of pulmonary sarcoidosis with elevated serum CEA.

Key Words: Sarcoidosis, Pulmonary, Tumor Markers, Biological, Carcinoembryonic Antigen