Serum Concentrations of Vitamine D Metabolites in Patients with Untreated Tuberculosis

Lee, Suk Hoon; Jung, Ho Yeon; Choi, Chul Jun; Yoo, Jee Hong; Kang, Hong Mo; Kim, Won Dong

doi:1988.35.4.256

Tuberc Respir Dis > Volume 35(4); 1988 > Article

Original Article

Tuberculosis and Respiratory Diseases 1988;35(4):256-261.
DOI: https://doi.org/10.4046/trd.1988.35.4.256 Published online December 1, 1988.

Serum Concentrations of Vitamine D Metabolites in Patients with Untreated Tuberculosis

Suk Hoon Lee, Ho Yeon Jung, Chul Jun Choi, Jee Hong Yoo, Hong Mo Kang, Won Dong Kim

Department of Internal Medicine, Kyung Hee University, School of Medicine, Seoul, Korea

한국인 결핵환자에서 비타민 D 대사물의 혈청농도

이석훈, 정호연, 최철준, 유지홍, 강홍모, 김원동

Abstract

T o evaluate the status of serum vitamin D metabolites in patients with untreated tuberculosis, the serum levels of 25-OHD₃ and 1.25-(OH)₂D₃ in 20 patients with untreated pulmonary tuberculosis and tuberculous pleurisy were compared with those in age and sex matched 20 healthy controls. The results were as follows; 1) Mean serum 25-OHD₃ concentrations in tubercul osis and control group were 14.6±7.5 ng/ ml and 15.0±5.0 ng/ ml respectively, and there was no significant difference (P > 1.0). 2) Mean serum 1.25-(OH)₂D₃ concentrations in tubercul osis a nd control group were 28.5±9.8 pg/ ml and 30.2±10.3 pg/ ml respectively, a nd there was no significant di fference (P > 1.0). 3) Mean serum 25-OHD₃ concentration in patients with tuberculous pleurisy was significantly lower than that in control subjects (P < 0.05). This study suggested that there was no significant association between tuberculosis and serum vitamin D metabolites in Korean patients, but vitamin D might be associated with tuberculous pleurisy.