A Study on Angiotensin Converting Enzyne Activity in Pulmonary Tuberculosis

Kee, Mahn Deok; Woo, Joon Hee; Shim, Young Soo

doi:1987.34.3.240

Tuberc Respir Dis > Volume 34(3); 1987 > Article

Original Article

Tuberculosis and Respiratory Diseases 1987;34(3):240-245.
DOI: https://doi.org/10.4046/trd.1987.34.3.240 Published online September 1, 1987.

A Study on Angiotensin Converting Enzyne Activity in Pulmonary Tuberculosis

Mahn Deok Kee, Joon Hee Woo, Young Soo Shim

Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea

폐결핵 환자에서 혈청 ACE활성도에 관한 연구

기만덕, 우준희, 심영수

Abstract

Serum angiotensin converting enzyme(ACE) activity was measured monthly for average 9 months during antituberculous chemotherapy to evaluate the effect of treatment on serum ACE activity. The serum ACE level of 12 nonmiliary pulmonary tuberculosis patients and 20 normal control subjects were 3.38 ± 2.07 u/ml(mean±S.D.) and 4.59±1.65 u/ml respectively The serum ACE activity seems to be apparently lower in the patient group than in the control group. but without significant statistical difference(p > 0.05) There was no statistically significant alteration of serum ACE activity during 9 month antituberculous chemotherapy in 12 nonmiliary pulmonary tuberculosis patients(p > 0.05). We concluded that the serum ACE activity is not a useful indicator for the evaluation of clinical status in pulmonary tuberculosis patients during chemotherapy.