Tuberc Respir Dis > Volume 40(5); 1993 > Article
Tuberculosis and Respiratory Diseases 1993;40(5):540-547.
DOI: https://doi.org/10.4046/trd.1993.40.5.540    Published online October 1, 1993.
Change of volume of isoflow in pneumoconiosis patients with small opacity.
Sang Yong Oh, Jee Won Kim, Chang Young Jung, Kyung Ah Kim, Im Goung Yun
Department of Occupational Disease, Chatholic University College, Seoul, Korea
Abstract
Backgrounds
The measurement of volume of isoflow has been considered as a sensitive test for detecting small airway diseases showing normal pulmonary function in a routine pulmonary function test. To evaluate the functions of small airway among dust exposed workers, the changes of volume of isoflow were measured and its applicability of managing early stage pneumoconiosis patients was studied.
Method
The subjects were 67 male, pneumoconiosis with small opacity and FEV1 > 80% , FEV1 ; FVC>75% in spirometry and the controls were 20 male, no dust-exposed office workers. The maximal epiratory volume curves after inhalation of indoor air and He-O2, gas mixtures were measured and ΔVmax50 , ΔVmax75, Viso V / VC between the dust exposed and control workers were compaired.
Results
1) There were no significant differences between two group in ΔVmax50 and ΔVmax75. But the ratio of VisoV / VC of the subjects was siginificantly higher than that of the control (p < 0.01). This study confirms that Viso V / VC is a veη useful index in early detection of small airway dysfunction. 2) The ratio of VisoV/ VC of the subjects was signigicantly different between only smoker group and mixed group (smoker and nonsmoker) . It suggestes that smoking is an important cousative factor of small airway dysfunction 3) As the profusion of the chest X-ray increased, the rartio of Viso V / VC increased , but no significant difference of VisoV/C was found between categories of pneumoconiosis. The categories of pneumoconiosis and small airway dysfunction may not be related 4) No significant relationship was established between the duration of w ork and the ratio of VisoV/VC.
Conclusions
: It is concluded that the measurement of VisoV/VC is useful to detect small airway dysfunction of early stage pneumoconiosis patents with small opacities but showing normal pulmonary function in a routine pulmonary function test.
Key Words: Pneumoconiosis, Volume of Isoflow


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