A case of lymphocytic interstitial pneumonitis.

Jung, Hee Jin; Cho, Eun Rae; Shim, Jae Jung; In, Kwang Ho; Yu, Sae Hwa; Kang, Kyung Ho; Won, Nam Hee; Choi, Young Ho

doi:1993.40.5.602

Tuberc Respir Dis > Volume 40(5); 1993 > Article

Case Report

Tuberculosis and Respiratory Diseases 1993;40(5):602-609.
DOI: https://doi.org/10.4046/trd.1993.40.5.602 Published online October 1, 1993.

A case of lymphocytic interstitial pneumonitis.

Hee Jin Jung, Eun Rae Cho, Jae Jung Shim, Kwang Ho In, Sae Hwa Yu, Kyung Ho Kang, Nam Hee Won, Young Ho Choi

¹Department of Internal Medicine, College of Medicine Korea University, Seoul, Korea
²Department of Pathology, College of Medicine Korea University, Seoul, Korea
³Department of Thoracic Surgery, College of Medicine Korea University, Seoul, Korea

Abstract

Lymphocytic interstitial pneumonitis (LIP) is one of parenchymal pulmonary infiltrative diseases first described at 1966 by Carrington and Liebow. In LIP, there is a predominance of mature small lymphocytes in the interstitium of the lung which form germinal centers. The disease process surrounds, but dose not invade lung parenchyma, tracheobronchial tree and vascular structures. The etiology remains sti1l unknown and the clinical features of this disorder have not been clearly defined. Therefore, the therapeutic modality is obscure. Development of LIP association with AIDS is often reported currently and possibility of progress to malignant lymphoma is emphasized. We experienced a case of primary LIP with pnemomediastinum. She was adimitted due to chest and anterior nuchal pain with chronic coughing, and diagnosed as pneumomediastinum with LIP. Medication with steroid was begun and some improvement of symptoms was observed, but an X-ray film of the chest remained same without improvement. We report above case with review of the literatures.

Key Words: Lymphocytic Interstitial Pneumonitis (LIP), Malignant lymphoma, Therapeutic modality