Tuberc Respir Dis > Volume 41(6); 1994 > Article
Tuberculosis and Respiratory Diseases 1994;41(6):644-650.
DOI: https://doi.org/10.4046/trd.1994.41.6.644    Published online December 1, 1994.
Familial Sarcoidosis, The First Report in Korea.
Wan Sik Uhm, Chae Man Lim, Woo Sung Kim, Dong Soon Kim, Won Dong Kim
Abstract
Sarcoidosis can affect two or more members of the same family, and the reported occurrence of such familial sarcoidosis is variable from 0.5 to 14%. Recently we have experienced familial sarcoidosis affected mother and daughter, for the first time in Korea. Mother was diagnosed as Stage II sarcoidosis 4 years ago by transbronchial lung biopsy and cervical lymph node biopsy with compatible BAL finding in our hospital. This time, the daughter was admitted with bilateral hilar enlargement and anterior uveitis. Even though she had positive tuberculin skin test and atypical BAL finding(lymphocyte: 61%, CD4/CD8: 1.22). Transbronchial lung biopsy and mediastinal lymph node biopsy revealed noncaseating epithelioid granulorna without AFB. Slit lamp examination of the eyes showed severe anterior uveitis. Systemic steroid therapy was started due to progressive uveitis with antituberculous medication.
Key Words: Familial sarcoidosis


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