Tuberc Respir Dis > Volume 42(5); 1995 > Article
Tuberculosis and Respiratory Diseases 1995;42(5):737-743.
DOI: https://doi.org/10.4046/trd.1995.42.5.737    Published online October 1, 1995.
A Comparative Study of Endotracheal Aspirates and Protected Specimen Brush in the Quantitative Cultures of the Ventilator-Associated Pneumonia.
Kyoung Ryeol Roo, Min Gu Kim, Gi Yang Kim, Ho Gyeong Jung, Young Ho Park, Byeng Sun Kang, Ho Chul Kim, Young Sil Hwang
Department of Internal Medicine, Gyeoungsang National University Collage of Medicine, Chinju, Korea.
Abstract
BACKGROUND
Pneumonia is a frequent complication in patients undergoing mechanical ventilation. Quantitative culture of protected specimen brush(PSB) have shown satisfactory diagnostic accuracy for the diagnosis of ventilator-associated pneumonia. However PSB method is invasive, expensive, and require a bronchoscopic procedure. But endotracheal aspiration(EA) is simple and less expensive. The purpose of our study was to investigate the diagnosic value of EA quantitative cultures. METHOD: We studied 15 cases of ventilator-associated pneumonia(for >72h of mechanical ventilation) patients. Patients were divided into two diagnostic categories. Group I was the patients who were suspicious of clinical pneumonia, Group II was the patients for control. The obtained samples by EA and PSB were homogenized for quantitative culture with a calibrated loop method in all patients. RESULT: Using 103cfu/ml, 105cfu/ml as threshold in quantitative culture of PSB, EA respectively, we found that EA quantitative cultures represented a relatively sentive(70%) and relatively specific (60%) method to diagnose the ventilator-associated pneumonia. CONCLUSION: Although EA quantitative cultures are less specific than PSB for diagnosing ventilator-associated pneumonia. EA quantitative cultures correlated with PSB quantitative culture in patients with clinical pneumonia and may be used to treat these patients when bronchoscopic procedures are not available.
Key Words: Ventilator-associated pneumonia, Endotracheal aspirate, Protected brush specimen, Quantitative cultures


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