A Case of Wegener's granulomatosis with obstruction of both anterior tibial and peroneal arteries.

Lee, Sang Hak; Yang, Dong Gyoo; Cho, Hyun Myung; Song, Kun Hoon; Park, Jae Min; Yoo, Jung Sun; Chang, Joon; Kim, Sung Kyu; Lee, Won Young; Shin, Dong Hwan

doi:1996.43.5.779

Tuberc Respir Dis > Volume 43(5); 1996 > Article

Case Report

Tuberculosis and Respiratory Diseases 1996;43(5):779-785.
DOI: https://doi.org/10.4046/trd.1996.43.5.779 Published online October 1, 1996.

A Case of Wegener's granulomatosis with obstruction of both anterior tibial and peroneal arteries.

Sang Hak Lee, Dong Gyoo Yang, Hyun Myung Cho, Kun Hoon Song, Jae Min Park, Jung Sun Yoo, Joon Chang, Sung Kyu Kim, Won Young Lee, Dong Hwan Shin

¹Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
²Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Wegener's granulomatosis is characterized by necrotizing granulomatous vasculitis affecting upper and lower respiratory tracts and kidneys. Vascular lesions commonly involve capillaries and small vessels but, less commonly larger vessels. We report a 46-year-old male patient of Wegener's granulomatosis associated with paranasal sinusitis, pulmonary consolidations, glomerulonephritis, skin lesions with obstruction of both anterior tibial and peroneal arteries. Several necrotic lesions of the toes had progressed to gangrene and both transmetatarsal amputations were done. The patient continued to receive cyclophosphamide and prednisolone.

Key Words: Wegener's granulomatosis, arterial obstruction