A Case of Fulminant Bronchiolitis Obliterans Organizing Pneumonia.

Kim, Mi Seon; Chang, Jung Hyun; Kim, Tai Hee; Cha, Ju Hyun; Kim, Hae Young; Sung, Sun Hee

doi:1998.45.1.204

Tuberc Respir Dis > Volume 45(1); 1998 > Article

Case Report

Tuberculosis and Respiratory Diseases 1998;45(1):204-212.
DOI: https://doi.org/10.4046/trd.1998.45.1.204 Published online February 1, 1998.

A Case of Fulminant Bronchiolitis Obliterans Organizing Pneumonia.

Mi Seon Kim, Jung Hyun Chang, Tai Hee Kim, Ju Hyun Cha, Hae Young Kim, Sun Hee Sung

¹Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.
²Department of Diagnostic Radiology, College of Medicine, Ewha Womans University, Seoul, Korea.
³Department of Anatomic Pathology, College of Medicine, Ewha Womans University, Seoul, Korea.

Abstract

Bronchiolitis obliterans organizing pneumonia(BOOP) is a type of diffuse interstitial lung disease that has emerged in the past decade as an important cause of acute respiratory illness in adult. Clinically, the entity usually starts with a subacute influenza-like illness, followed by cough, progressive dyspnea, and weight loss. Organized inflammatory polypoid materials predominantly affecting distal bronchioles, alveolar ducts, and peribronchial alveolar spaces are a key pathologic findings. BOOP is characterized by a good response to glucocorticoid and an excellent prognosis. However, there is a subset of BOOP who presents with a fulminant course leading to death or chronic severe fibrosis with marked impairment of lung function. Recently, we have experienced a case of rapidly progressive BOOP, diagnosed by open lung biopsy and showed a reluctant response to corticosteroid.

Key Words: Rapidly progressive bronchiolitis obliterans organizing pneumonia