Tuberc Respir Dis > Volume 57(4); 2004 > Article
Tuberculosis and Respiratory Diseases 2004;57(4):329-335.
DOI: https://doi.org/10.4046/trd.2004.57.4.329    Published online October 1, 2004.
The SOFA Score to Evaluate Organ Failure and Prognosis in the Intensive Care Unit Patients.
Su Ho Kim, Myung Goo Lee, Sang Myeon Park, Young Bum Park, Seung Hun Jang, Cheol Hong Kim, Man Jo Jeon, Tae Rim Shin, Kwang Seok Eom, In Gyu Hyun, Ki Suck Jung, Seung Joon Lee
1Department of Internal Medicine, College of Medicine, Hallym university, Chuncheon, Korea. mglee@hallym.or.kr
2Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea.
Abstract
BACKGROUND
The Sequential Organ Failure Assessment (SOFA) score can help to assess organ failure over time and is useful to evaluate morbidity. The aim of this study is to evaluate the performance of SOFA score as a descriptor of multiple organ failure in critically ill patients in a local unit hospital, and to compare with APACHE III scoring system. METHODS: This study was carried out prospectively. A total of ninety one patients were included who admitted to the medical intensive care unit (ICU) in Chuncheon Sacred Heart Hospital from May 1 through June 30, 2000. We excluded patients with a length of stay in the ICU less than 2 days following scheduled procedure, admissions for ECG monitoring, other department and patients transferred to other hospital. The SOFA score and APACHE III score were calculated on admission and then consecutively every 24 hours until ICU discharge. RESULTS: The ICU mortality rate was 20%. The non-survivors had a higher SOFA score within 24 hours after admission. The number of organ failure was associated with increased mortality. The evaluation of a subgroup of 74 patients who stayed in the ICU for at least 48 hours showed that survivors and non-survivors followed a different course. In this subgroup, the total SOFA score increased in 81% of the non-survivors but in only 21% of the survivors. Conversely, the total SOFA score decreased in 48% of the survivors compared with 6% of the non-survivors. The non-survivors also had a higher APACHE III score within 24 hours and there was a correlation between SOFA score and APACHE III score. CONCLUSION: The SOFA score is a simple, but effective method to assess organ failure and to predict mortality in critically ill patients. Regular and repeated scoring enables patient's condition and clinical course to be monitored and better understood. The SOFA score well correlates with APACHE III score.
Key Words: APACHE III, Intensive Care Unit, Multiple Organ failure, Sequential Organ Failure Assessment (SOFA)


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