Tuberc Respir Dis > Volume 62(5); 2007 > Article
Tuberculosis and Respiratory Diseases 2007;62(5):427-431.
DOI:    Published online May 1, 2007.
A Case of Bronchus-Associated Lymphoid Tissue(BALT) Lymphoma Treated with Lobectomy.
Won Sub Choi, Jae Hyun Cho, Young Il Hwang, Seung Hun Jang, Dong Gyu Kim, Sun Young Jun, Kwangseon Min, In Jae Lee, Jae Woong Lee, Ki Suck Jung
1Division of Pulmonary, Allergy and Critical Care Medicine of Hallym University Medical Center, Korea.
2Department of Pathology, Hallym University College of Medicine, Anyang, Korea.
3Department of Radiology, Hallym University College of Medicine, Anyang, Korea.
4Department of Thorasic and Cardiovascular Surgery Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
The bronchus-asociated lymphoid tissue(BALT) lymphoma is a low-grade primary malignant lymphoma that originates from bronchus associated lymphoid tissue. A 67-year-old woman was admitted for evaluation of cough, sputum, rhinorrhea which had persisted for one month. Physical examination showed decreased breathing sound on the left upper lung field. High resolution chest computed tomography demonstrated consolidation which showed air-bronchogram and surrounding ground glass opacity in left upper lobe. These findings implicated inactive tuberculosis, organizing pneumonia, or bronchiolo-alveolar carcinoma. The histologic findings from percutaneous needle aspiration biopsy revealed aggregated atypical small lymphoid cells with lymphoepithelial lesions. With immunohistochemical staining, the atypical lymphoid cells reacted positively with CD 20 antibody and negatively with CD 3 antibody. Thus, we could diagnosed her as a patient with BALT lymphoma. After left upper lobectomy, she has been well without recurrence of the disease for 14 months. In this country of Republic of Korea, it was the 1st case of BALT lymphoma surgically treated when histological diagnosis had been done. Based on this case, we wanted to demonstrate the importance of early histological diagnosis and treatment of BALT lymphoma.
Key Words: BALT, Lung, Mucossa-associated lymphoid tissue (MALT) lymphoma

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