A Case of Acute Myeloid Leukemia with Multilineage Dysplasia accompanying Malignant Pleural Effusion.

Seo, Young Ik; Choi, Tae Youn; Shin, Jeong Won; Won, Jong Ho; Lee, Sang Cheol; Park, Hee Sook; Lee, Nam Soo; Park, Rojin

doi:2008.65.1.49

Tuberc Respir Dis > Volume 65(1); 2008 > Article

Case Report

Tuberculosis and Respiratory Diseases 2008;65(1):49-51.
DOI: https://doi.org/10.4046/trd.2008.65.1.49 Published online July 1, 2008.

A Case of Acute Myeloid Leukemia with Multilineage Dysplasia accompanying Malignant Pleural Effusion.

Young Ik Seo, Tae Youn Choi, Jeong Won Shin, Jong Ho Won, Sang Cheol Lee, Hee Sook Park, Nam Soo Lee, Rojin Park

¹Department of Clinical Pathology, College of Medicine, Soon Chun Hyang University, Seoul, Korea. rpark@hosp.sch.ac.kr
²Department of Internal Medicine, College of Medicine, Soon Chun Hyang University, Seoul, Korea.

Abstract

We report a case of acute myeloid leukemia with multilineage dysplasia accompanying malignant pleural effusion. A 73 year-old male patient was admitted complaining of febrile sensations and right chest pain. The cytology of the pleural fluid revealed malignant pleural effusion showing many blasts, which had previously been identified in his bone marrow when he was diagnosed with acute myeloid leukemia with multilineage dysplasia two months earlier. His age and poor general condition had precluded chemotherapy with the exception of hydroxyurea and conservative treatment. Unfortunately, he succumbed to the disease 4.5 months after diagnosis. This case highlights the importance of determining if the pleural effusion of acute leukemia is malignant or not because it can suggest a pleural metastasis and influence the prognosis.

Key Words: Malignant pleural effusion, Acute myeloid leukemia with multilineage dysplasia, Extramedullary involvement