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Original Article
COPD
Predictors of Suboptimal Peak Inspiratory Flow in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Clinical Practice
Natalia V. Trushenko, Baina B. Lavginova, Svetlana Yu. Chikina, et al.
Tuberc Respir Dis. 2025;88(3):516-525.   Published online March 6, 2025
Background: Incorrect inhalation technique is a primary cause of therapeutic failure in chronic obstructive pulmonary disease (COPD), leading to increased exacerbation frequency. Identifying predictors of suboptimal peak inspiratory flow (sPIF) can significantly enhance treatment efficacy in COPD patients. The objective of this study was to identify the prevalence and predictors of sPIF in hospitalized patients with acute exacerbation of COPD...
Original Article
COPD, Pulmonary Infection
Effects of Vaccination on Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Nationwide Population-Based Cohort Study
Sang Hyuk Kim, Hyun Lee, Min Ji Kim, et al.
Tuberc Respir Dis. 2025;88(3):526-534.   Published online February 27, 2025
Background: Coronavirus disease 2019 (COVID-19) vaccination may offer benefits for patients with chronic obstructive pulmonary disease (COPD). However, the evidence on whether the vaccination decreases the frequency of acute exacerbation of COPD (AECOPD) is limited. Methods: This study enrolled 41,606 individuals diagnosed with COPD using the Korean National Health Insurance System-severe acute respiratory syndrome coronavirus 2 (NHIS SARS-CoV-2) database between 2020...
Original Article
COPD
Maximal Forced Inspiratory Flow Dynamics and Acute Exacerbation in Chronic Obstructive Pulmonary Disease Patients with Exacerbation History
Heemoon Park, Jung-Kyu Lee, Eun Young Heo, et al.
Tuberc Respir Dis. 2025;88(3):535-544.   Published online March 28, 2025
Background: Chronic obstructive pulmonary disease (COPD), characterized by progressive airflow obstruction and frequent exacerbations, is a significant global health burden. COPD severity has traditionally been assessed using expiratory flow measurements, like forced expiratory volume in 1 second. However, the role of inspiratory flow, specifically maximal forced inspiratory flow (FIFmax), in predicting exacerbation risk is gaining attention. Methods: This retrospective cohort study...
Original Article
Lung Cancer
Tissue Adequacy and Diagnostic Yield Assessment in Malignant Lymph Nodes Using Endobronchial Ultrasound (EBUS)-Guided Miniforcep Biopsy vs. EBUS-Guided Transbronchial Needle Aspiration
Pipu Tavornshevin, Poonchavist Chantranuwatana, Vorawut Thanthitaweewat, et al.
Tuberc Respir Dis. 2025;88(3):545-556.   Published online April 3, 2025
Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a predominantly used method for lymph node (LN) metastasis assessment. This study aims to identify tissue adequacy improvement with the addition of EBUS-guided miniforcep biopsy (EBUS-MFB) to EBUS-TBNA in sampling LNs. Methods: We assessed tissue adequacy in patients with mediastinal and hilar lymphadenopathy, comparing the combination of EBUS-MFB and EBUS-TBNA with EBUS-TBNA alone....
Original Article
Critical Care Medicine
Determinants of Limiting Life-Sustaining Treatment in Critically Ill COVID-19 Patients: A Multicenter Study in Korean Intensive Care Units
I Re Heo, Tae Hoon Kim, Won Jai Jung, et al.
Tuberc Respir Dis. 2025;88(3):557-565.   Published online April 28, 2025
Background: Understanding of the life-sustaining treatment (LST) decisions in critically ill coronavirus disease 2019 (COVID-19) patients remains limited. This study aimed to identify factors influencing LST decisions, and compare clinical outcomes between patients with, and without, LST. Methods: This multicenter, retrospective cohort study analyzed data from 1,081 COVID-19 patients admitted to intensive care units (ICUs) across Korea from January 1, 2020,...
Original Article
Tuberculosis
Tuberculosis Care Quality Assessment: Evaluating Diagnosis and Treatment Effectiveness in Korea, 2018 to 2022
Kang-Mo Gu, Jinsoo Min,
Tuberc Respir Dis. 2025;88(3):566-574.   Published online May 19, 2025
Background: Tuberculosis (TB) care quality assessment has been implemented in the Republic of Korea since 2018. This paper evaluates the results of six rounds of the quality assessment from 2018 to 2023, focusing on the sixth quality assessment in 2023. Methods: This study used cross-linked databases from the Health Insurance Review and Assessment Service, the Korea Disease Control and Prevention Agency,...
Original Article
Pleural Diseases
Efficacy of Portable Ultrasonography for Early Detection of Pneumothorax Following Lung Biopsy
Won Gun Kwack, Manbong Heo, Yeonseok Choi, et al.
Tuberc Respir Dis. 2025;88(3):575-582.   Published online February 27, 2025
Background: Pneumothorax is a notable complication of lung biopsy, and its early detection is crucial. This study aimed to compare the sensitivities of handheld portable lung ultrasonography and chest radiography in identifying early pneumothorax post-lung biopsy. Methods: Upright chest radiography and lung ultrasonography were conducted at 3 and 24 hours following lung biopsy. The disappearance of lung sliding and the appearance...
Original Article
Miscellaneous
Efficacy and Safety of YJP-40 in Patients with Acute Bronchitis: A Randomized, Double-Blind, Parallel Group Study
Chin Kook Rhee
Tuberc Respir Dis. 2025;88(3):583-590.   Published online March 20, 2025
Background: Pelargonium sidoides has been known to be effective in treating respiratory diseases. P. sidoides extract (Umckamin®, Han Wha Pharmaceuticals) was approved in Korea for acute bronchitis. YJP-40 (Umckamin plus®) is formulated with extract of P. sidoides and ivy leaf. Ivy leaf extract has an expectorant effect and has been used to treat bronchitis. The aim of this study was...
Original Article
Miscellaneous
Unbalanced Associations between Physical, Psychological, and Social Domains of the Leicester Cough Questionnaire: Network and Mediation Analyses
Jieun Kang, Jiyeon Kang, Sung Jun Chung, et al.
Tuberc Respir Dis. 2025;88(3):591-598.   Published online May 26, 2025
Background: The Leicester Cough Questionnaire (LCQ) is a validated instrument for evaluating cough-related impairments within three domains: physical, psychological, and social. This study investigated how the physical, psychological, and social domains of chronic cough are interrelated using the LCQ. Methods: Adult patients with chronic cough from 16 respiratory centers who completed the LCQ and underwent diagnostic workup were retrospectively reviewed. Spearman's...
Current Issue
Volume 88(3); Jul 2025
Reviews
COPD
4936
Challenges and the Future of Pulmonary Function Testing in Chronic Obstructive Pulmonary Disease (COPD): Toward Earlier Diagnosis of COPD
Sang Hyuk Kim, MeiLan K. Han
Tuberc Respir Dis. 2025;88(3):413-418.   Published online March 25, 2025
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4932
Non-pharmacologic Prevention of Acute Exacerbation Chronic Obstructive Pulmonary Disease
Joon Young Choi
Tuberc Respir Dis. 2025;88(3):419-430.   Published online March 7, 2025
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Lung Cancer
4937
Emerging Role of Molecular Testing in the Management of Non-metastatic Non-small Cell Lung Cancer
Hidenori Kage
Tuberc Respir Dis. 2025;88(3):431-441.   Published online March 26, 2025
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4942
Integration of Liquid Biopsy for Optimal Management of Non-small Cell Lung Cancer
Yuko Oya, Ichidai Tanaka, Ross A. Soo
Tuberc Respir Dis. 2025;88(3):442-453.   Published online April 8, 2025
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Interstitial Lung Disease
4934
Korean Guidelines for the Diagnosis and Management of Interstitial Lung Disease: Other Forms of Interstitial Lung Disease
Hyung Koo Kang, Sun Mi Choi, Hong-Joon Shin, Hae In Jung, Uiri An, Sei Hoon Yang
Tuberc Respir Dis. 2025;88(3):454-476.   Published online March 13, 2025
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4933
Korean Guidelines for Diagnosis and Management of Interstitial Lung Disease: Cryptogenic Organizing Pneumonia
Yong Suk Jo, Jong Sun Park, Sun Hyo Park, Joon Sung Joh, Hye Jin Jang, Hyun-Kyung Lee
Tuberc Respir Dis. 2025;88(3):477-487.   Published online March 13, 2025
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4939
Korean Guidelines for the Diagnosis and Management of Interstitial Lung Diseases: Sarcoidosis
Eun Joo Lee, Yangjin Jegal, Dong Won Park, Jimyung Park, Jun-Pyo Myong, Ji-Hyun Lee, Bo Hyoung Kang
Tuberc Respir Dis. 2025;88(3):488-503.   Published online April 1, 2025
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4931
Korean Guidelines for the Diagnosis and Management of Interstitial Lung Diseases: Hypersensitivity Pneumonitis
Byoung Soo Kwon, Sooim Sin, Kyung Hoon Kim, Jinkyeong Park, Beomsu Shin, Hongseok Yoo, Yong Hyun Kim
Tuberc Respir Dis. 2025;88(3):504-515.   Published online March 6, 2025
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Original Articles
COPD
4930
Predictors of Suboptimal Peak Inspiratory Flow in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Clinical Practice
Natalia V. Trushenko, Baina B. Lavginova, Svetlana Yu. Chikina, Natalia E. Obukhova, Iuliia A. Levina, Fedor D. Tkachenko, Galina V. Nekludova, Zamira M. Merzhoeva, Sergey N. Avdeev
Tuberc Respir Dis. 2025;88(3):516-525.   Published online March 6, 2025
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COPD, Pulmonary Infection
4929
Effects of Vaccination on Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Nationwide Population-Based Cohort Study
Sang Hyuk Kim, Hyun Lee, Min Ji Kim, Min Gu Kang, Jong Seung Kim, Jong Geol Jang, Youlim Kim, Hyeon-Kyoung Koo, Chin Kook Rhee, Kyung Hoon Min, Yong Il Hwang, Deog Kyeom Kim, Yong Bum Park, Ji-Yong Moon
Tuberc Respir Dis. 2025;88(3):526-534.   Published online February 27, 2025
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COPD
4938
Maximal Forced Inspiratory Flow Dynamics and Acute Exacerbation in Chronic Obstructive Pulmonary Disease Patients with Exacerbation History
Heemoon Park, Jung-Kyu Lee, Eun Young Heo, Deog Kyeom Kim, Hyun Woo Lee
Tuberc Respir Dis. 2025;88(3):535-544.   Published online March 28, 2025
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Lung Cancer
4941
Tissue Adequacy and Diagnostic Yield Assessment in Malignant Lymph Nodes Using Endobronchial Ultrasound (EBUS)-Guided Miniforcep Biopsy vs. EBUS-Guided Transbronchial Needle Aspiration
Pipu Tavornshevin, Poonchavist Chantranuwatana, Vorawut Thanthitaweewat, Virissorn Wongsrichanalai, Thitiwat Sriprasart, Nophol Leelayuwatanakul
Tuberc Respir Dis. 2025;88(3):545-556.   Published online April 3, 2025
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Critical Care Medicine
4944
Determinants of Limiting Life-Sustaining Treatment in Critically Ill COVID-19 Patients: A Multicenter Study in Korean Intensive Care Units
I Re Heo, Tae Hoon Kim, Won Jai Jung, Gil Myeong Seong, Sun Jung Kwon, Jae Young Moon, Song-I Lee, Do Sik Moon, Tae-Ok Kim, Chul Park, Eun Young Choi, Jung-Wan Yoo, Sunghoon Park, Ae Rin Baek, Sung Yoon Lim, Jung Soo Kim, Jongmin Lee, Chi Ryang Chung, Sang-Min Lee, Su Hwan Lee, Moon Seong Baek, Jin Won Huh, Woo Hyun Cho, Ho Cheol Kim
Tuberc Respir Dis. 2025;88(3):557-565.   Published online April 28, 2025
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Tuberculosis
4947
Tuberculosis Care Quality Assessment: Evaluating Diagnosis and Treatment Effectiveness in Korea, 2018 to 2022
Kang-Mo Gu, Jinsoo Min
Tuberc Respir Dis. 2025;88(3):566-574.   Published online May 19, 2025
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Pleural Diseases
4928
Efficacy of Portable Ultrasonography for Early Detection of Pneumothorax Following Lung Biopsy
Won Gun Kwack, Manbong Heo, Yeonseok Choi, Cheon Woong Choi, Byoung Soo Kwon, Yeon Wook Kim, Jong Sun Park, Young-Jae Cho, Jae Ho Lee, Sung Yoon Lim
Tuberc Respir Dis. 2025;88(3):575-582.   Published online February 27, 2025
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Miscellaneous
4935
Efficacy and Safety of YJP-40 in Patients with Acute Bronchitis: A Randomized, Double-Blind, Parallel Group Study
Chin Kook Rhee
Tuberc Respir Dis. 2025;88(3):583-590.   Published online March 20, 2025
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4948
Unbalanced Associations between Physical, Psychological, and Social Domains of the Leicester Cough Questionnaire: Network and Mediation Analyses
Jieun Kang, Jiyeon Kang, Sung Jun Chung, Hyung Koo Kang, Sung-Soon Lee, Yun-Jeong Jeong, Ji-Yong Moon, Deog Kyeom Kim, Jin Woo Kim, Seung Hun Jang, Jae-Woo Kwon, Byung-Jae Lee, Hyeon-Kyoung Koo
Tuberc Respir Dis. 2025;88(3):591-598.   Published online May 26, 2025
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Letters to the Editor
Asthma
4943
Enhancing Asthma Management: Key Insights from the 10th Asthma Quality Assessment Program
Youlim Kim, Jong Geol Jang, Tai Joon An, Joon Young Choi, Chin Kook Rhee, Kyung Hoon Min, Yong Il Hwang
Tuberc Respir Dis. 2025;88(3):599-602.   Published online April 15, 2025
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Critical Care Medicine
4940
The Quality Changes in Intensive Care Units in South Korea since the Initiation of Intensive Care Unit Quality Assessments
Su Hwan Lee, Sunghoon Park
Tuberc Respir Dis. 2025;88(3):603-605.   Published online April 1, 2025
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Tuberculosis
4946
Tuberculosis Notification and Incidence: Republic of Korea, 2023
Jinsoo Min, Yoolwon Jeong, Hyung Woo Kim, Ju Sang Kim
Tuberc Respir Dis. 2025;88(3):606-609.   Published online May 19, 2025
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Pulmonary Infection
4945
Epidemiology of Severe Acute Respiratory Infection in Korea: 2022 to 2024 Surveillance Data
Young Seok Lee, Hye Sun Lee, Jae Young Moon
Tuberc Respir Dis. 2025;88(3):610-613.   Published online April 28, 2025
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Tuberculosis and
Respiratory Diseases

Print ISSN: 1738-3536
Online ISSN: 2005-6184

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