Original Article
COPD
Effects of Farinelli Breating Exercise on Respiratory Function and Symptoms in Patients with Chronic Obstructive Pulmonary Disease
Supawit Ittinirundorn, Naiyana Wongsaita, Dujrath Somboonviboon, et al.
Tuberc Respir Dis. 2022;85(2):137-146.   Published online December 29, 2021
Background: Farinelli breathing (FB) exercise is a typical breathing exercise used by singers. This study aimed to compare effects of FB exercise and diaphragmatic breathing (DB) exercise on respiratory function and symptoms in patients with chronic obstructive pulmonary disease (COPD). Methods: Sixteen patients aged 51–80 years with mild or moderate COPD were recruited for this study. They were divided into two...
Original Article
Lung Cancer
Afatinib Mediates Autophagic Degradation of ORAI1, STIM1, and SERCA2, Which Inhibits Proliferation of Non–Small Cell Lung Cancer Cells
Mi Seong Kim, So Hui Kim, Sei-Hoon Yang, et al.
Tuberc Respir Dis. 2022;85(2):147-154.   Published online December 1, 2021
Background: The expression of calcium signaling pathway molecules is altered in various carcinomas, which are related to the proliferation and altered characteristics of cancer cells. However, changes in calcium signaling in anti-cancer drugresistant cells (bearing a T790M mutation in epidermal growth factor receptor [EGFR]) remain unclear. Methods: Afatinib-mediated changes in the level of store-operated Ca2+ entry (SOCE)-related proteins and intracellular Ca2+...
Original Article
Lung Cancer
Pretreatment Neutrophil-to-Lymphocyte Ratio and Smoking History as Prognostic Factors in Advanced Non–Small Cell Lung Cancer Patients Treated with Osimertinib
Ji Young Park, Seung Hun Jang, Chang Youl Lee, et al.
Tuberc Respir Dis. 2022;85(2):155-164.   Published online January 20, 2022
Background: The remarkable efficacy of osimertinib in non‒small cell lung cancer (NSCLC) with acquired T790M mutation has been widely documented in clinical trials and real-world practice. However, some patients show primary resistance to this drug. Even patients who initially show a favorable response have inconsistent clinical outcomes later. Therefore, the aim of this study was to identify additional clinical predictive...
Original Article
Tuberculosis
Assessment of Household Catastrophic Total Cost of Tuberculosis and Its Determinants in Cairo: Prospective Cohort Study
Manar M. Ellaban, Nashwa I. Basyoni, Dina N. K. Boulos, et al.
Tuberc Respir Dis. 2022;85(2):165-174.   Published online September 3, 2021
Background: One goal of the End tuberculosis (TB) Strategy is to see no TB-affected households experiencing catastrophic costs. Therefore, it is crucial for TB-elimination programs to identify catastrophic costs and their main drivers in order to establish appropriate health and social measures. This study aimed to measure the percent of catastrophic costs experienced by Egyptian TB patients and to identify...
Original Article
Tuberculosis
Pulmonary Functions and Inflammatory Biomarkers in Post-Pulmonary Tuberculosis Sequelae
Kumar Shanmugasundaram, Anjana Talwar, Karan Madan, et al.
Tuberc Respir Dis. 2022;85(2):175-184.   Published online March 2, 2022
Background: Post-tuberculosis (TB) sequelae is a commonly encountered clinical entity, especially in high TB burden countries. This may represent chronic anatomic sequelae of previously treated TB, with frequent symptomatic presentation. This pilot study was aimed to investigate the pulmonary functions and systemic inflammatory markers in patients with post-TB sequelae (PTBS) and to compare them with post-TB without sequelae (PTBWS) participants...
Original Article
Interstitial Lung Disease
Clinical Features, Diagnosis, Management, and Outcomes of Idiopathic Pulmonary Fibrosis in Korea: Analysis of the Korea IPF Cohort (KICO) Registry
Yangjin Jegal, Jong Sun Park, Song Yee Kim, et al.
Tuberc Respir Dis. 2022;85(2):185-194.   Published online December 13, 2021
Background: The Korea Interstitial Lung Disease Study Group has made a new nationwide idiopathic pulmonary fibrosis (IPF) registry because the routine clinical practice has changed due to new guidelines and newly developed antifibrotic agents in the recent decade. The aim of this study was to describe recent clinical characteristics of Korean IPF patients. Methods: Both newly diagnosed and following IPF patients...
Original Article
Critical Care Medicine
A Comprehensive Analysis of 5-Year Outcomes in Patients with Cancer Admitted to Intensive Care Units
Yoonki Hong, Woo Jin Kim, Ji Young Hong, et al.
Tuberc Respir Dis. 2022;85(2):195-201.   Published online January 20, 2022
Background: The aim of this study was to evaluate the long-term (5-year) clinical outcomes of patients who received intensive care unit (ICU) treatment using Korean nationwide data. Methods: All patients aged >18 years with ICU admission according to Korean claims data from January 2008 to December 2010 were enrolled. These enrolled patients were followed up until December 2015. The primary outcome...

Tuberculosis and
Respiratory Diseases

Print ISSN: 1738-3536
Online ISSN: 2005-6184


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