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Original Article
COPD, Asthma
Association of Nutritional Intake with Physical Activity and Handgrip Strength in Individuals with Airflow Limitation
I Re Heo, Tae Hoon Kim, Jong Hwan Jeong, et al.
Tuberc Respir Dis. 2025;88(1):120-129.   Published online October 11, 2024
Background: We investigated whether nutritional intake is associated with physical activity (PA) and handgrip strength (HGS) in individuals with airflow limitation. Methods: This study analyzed data from the 2014 and 2016 Korean National Health and Nutrition Examination Survey. We assessed total protein intake (g/day), caloric intake (kcal/day), and other nutritional intakes, using a 24-hour dietary recall questionnaire. HGS was measured three...
Original Article
Interstitial Lung Disease
Regenerative Capacity of Alveolar Type 2 Cells Is Proportionally Reduced Following Disease Progression in Idiopathic Pulmonary Fibrosis-Derived Organoid Cultures
Hyeon Kyu Choi, Gaeul Bang, Ju Hye Shin, et al.
Tuberc Respir Dis. 2025;88(1):130-137.   Published online September 27, 2024
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease that culminates in respiratory failure and death due to irreversible scarring of the distal lung. While initially considered a chronic inflammatory disorder, the aberrant function of the alveolar epithelium is now acknowledged as playing a central role in the pathophysiology of IPF. This study aimed to investigate the regenerative...
Original Article
Lung Cancer
KEAP1-NRF2 Pathway as a Novel Therapeutic Target for EGFR-Mutant Non-small Cell Lung Cancer
Jae-Sun Choi, Hye-Min Kang, Kiyong Na, et al.
Tuberc Respir Dis. 2025;88(1):138-149.   Published online September 23, 2024
Background: Kelch-like ECH-associated protein 1 (KEAP1)–nuclear factor erythroid- 2-related factor 2 (NRF2) pathway is a major regulator protecting cells from oxidative and metabolic stress. Studies have revealed that this pathway is involved in mediating resistance to cytotoxic chemotherapy and immunotherapy; however, its implications in oncogene-addicted tumors are largely unknown. This study aimed to elucidate whether this pathway could be a...
Original Article
Tuberculosis
Diagnostic Accuracy of BD MAX MDR-TB Assay Performed on Bronchoscopy Specimens in Patients with Suspected Pulmonary Tuberculosis
Sung Jun Ko, Kui Hyun Yoon
Tuberc Respir Dis. 2025;88(1):150-158.   Published online September 23, 2024
Background: Several novel molecular platforms using nucleic acid amplification tests have been developed for the diagnosis of pulmonary tuberculosis (PTB) and rapid detection of isoniazid and rifampin resistance. Among them, the BD MAX MDR-TB assay (BD MAX) has shown high sensitivity and specificity; however, its diagnostic accuracy performed on bronchoscopy specimens has not been reported. Methods: We retrospectively reviewed the medical...
Original Article
Tuberculosis
Clinical Profiles of Multidrug-Resistant and Rifampicin-Monoresistant Tuberculosis in Korea, 2018–2021: A Nationwide Cross-Sectional Study
Jinsoo Min, Yousang Ko, Hyung Woo Kim, et al.
Tuberc Respir Dis. 2025;88(1):159-169.   Published online September 23, 2024
Background: This study aimed to identify the clinical characteristics of multidrug-resistant/ rifampicin-resistant tuberculosis (MDR/RR-TB) in the Republic of Korea. Methods: Data of notified people with tuberculosis between July 2018 and December 2021 were retrieved from the Korea Tuberculosis Cohort database. MDR/RR-TB was further categorized according to isoniazid susceptibility as follows: multidrug-resistant tuberculosis (MDR-TB), rifampicin-monoresistant tuberculosis (RMR-TB), and RR-TB if susceptibility to...
Original Article
Tuberculosis
High-Dose Rifampicin for 3 Months after Culture Conversion for Drug-Susceptible Pulmonary Tuberculosis
Nakwon Kwak, Joong-Yub Kim, Hyung-Jun Kim, et al.
Tuberc Respir Dis. 2025;88(1):170-180.   Published online September 27, 2024
Background: This study aimed to determine whether a shorter high-dose rifampicin regimen is non-inferior to the standard 6-month tuberculosis regimen. Methods: This multicenter, randomized, open-label, non-inferiority trial enrolled participants with respiratory specimen positivity by Xpert MTB/RIF assay or Mycobacterium tuberculosis culture without rifampicin-resistance. Participants were randomized at 1:1 to the investigational or control group. The investigational group received high-dose rifampicin (30...
Original Article
Miscellaneous, Pleural Diseases
Dry Medical Thoracoscopy with Artificial Pneumothorax Induction Using Veress Needle
Nai-Chien Huan, Sze Shyang Kho, Larry Ellee Nyanti, et al.
Tuberc Respir Dis. 2025;88(1):181-189.   Published online November 14, 2024
Background: In the absence of significant pleural effusion, conventional medical thoracoscopy (MT) is often not feasible due to the risk of lung injury. Dry MT mitigates these risks by inducing artificial pneumothorax through needle insufflation or blunt dissection. Although the Veress needle is commonly used by surgeons to create pneumoperitoneum before laparoscopic surgeries, its application in dry MT has not...
Current Issue
Volume 88(1); Jan 2025
Original Articles
Better Chemotherapeutic Response of Small Cell Lung Cancer in Never Smokers than in Smokers
Ha-Young Park, Hyung-Joo Oh, Hwa Kyung Park, Joon-Young Yoon, Chang-Seok Yoon, Bo Gun Kho, Tae-Ok Kim, Hong-Joon Shin, Chul-Kyu Park, Yong-Soo Kwon, Yu-Il Kim, Sung-Chul Lim, Young-Chul Kim, In-Jae Oh
Received May 7, 2024   Accepted February 10, 2025   Published online February 11, 2025   
DOI: https://doi.org/10.4046/trd.2024.0056    [Epub ahead of print]
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Management of Chronic Obstructive Pulmonary Disease in Vietnam during the COVID-19 Period: Current Situation and Challenges
Thuy Thanh Phan, Giap Van Vu, Chau Quy Ngo
Received September 26, 2024   Accepted February 5, 2025   Published online February 7, 2025   
DOI: https://doi.org/10.4046/trd.2024.0140    [Epub ahead of print]
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Letters to the Editor
Authors’ Response: Additional Analyses of Nutritional Intake and Muscle Strength in Individuals with Airflow Limitation
I Re Heo, Ho Cheol Kim
Received December 3, 2024   Accepted January 11, 2025   Published online February 6, 2025   
DOI: https://doi.org/10.4046/trd.2024.0184    [Epub ahead of print]
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Original Articles
Adherence to Pharmacological Management Guidelines for Stable Chronic Obstructive Lung Disease
Sang Min Han, Hyo Seon Kim, Seung Yong Park, Heung Bum Lee, Young Bum Park, Chin Kook Rhee, Youlim Kim, Seoung Ju Park
Received September 10, 2024   Accepted February 5, 2025   Published online February 6, 2025   
DOI: https://doi.org/10.4046/trd.2024.0130    [Epub ahead of print]
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Reviews
Pharmacologic Therapies for Preventing Chronic Obstructive Pulmonary Disease Exacerbations: A Comprehensive Review
Hyun Woo Lee
Received November 6, 2024   Accepted February 3, 2025   Published online February 4, 2025   
DOI: https://doi.org/10.4046/trd.2024.0170    [Epub ahead of print]
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Original Articles
Kernel Conversion Improves the Correlation between the Extent of Emphysema and Clinical Parameters in Chronic Obstructive Pulmonary Disease: A Multicenter Cohort Study
Tai Joon An, Youlim Kim, Hyun Lee, Hyeon-Kyoung Koo, Naoya Tanabe, Kum Ju Chae, Kwang Ha Yoo
Received November 3, 2024   Accepted January 23, 2025   Published online February 4, 2025   
DOI: https://doi.org/10.4046/trd.2024.0166    [Epub ahead of print]
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Increased Neutrophil Elastase in Affected Lobes of Bronchiectasis and Correlation of Its Levels between Sputum and Bronchial Lavage Fluid
Lam Nguyen-Ho, Hoang Kim Tu Trinh, Vu Le-Thuong, Kieu Minh Le, Van Thanh Niem Vo, Diem My Vu, Ngoc Tran-Van, James D. Chalmers
Received May 14, 2024   Accepted January 13, 2025   Published online January 14, 2025   
DOI: https://doi.org/10.4046/trd.2024.0078    [Epub ahead of print]
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Reviews
Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Connective Tissue Disease Associated Interstitial Lung Disease
Ju Hyun Oh, Jae Ha Lee, Sung Jun Chung, Young Seok Lee, Tae-Hyeong Kim, Tae-Jung Kim, Joo Hun Park
Received October 1, 2024   Accepted January 6, 2025   Published online January 10, 2025   
DOI: https://doi.org/10.4046/trd.2024.0148    [Epub ahead of print]
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Korean Guidelines for Diagnosis and Management of Idiopathic Nonspecific Interstitial Pneumonia
Yong Suk Jo, Hyun-Kyung Lee, Sun Hyo Park, Joon Sung Joh, Hye Jin Jang, Jong Sun Park
Received November 4, 2024   Accepted December 30, 2024   Published online January 6, 2025   
DOI: https://doi.org/10.4046/trd.2024.0168    [Epub ahead of print]
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Original Articles
Relationship between the Geriatric Nutrition Risk Index and the Prognosis of Severe Coronavirus Disease 2019 in Korea
Hye Ju Yeo, Daesup Lee, Mose Chun, Jin Ho Jang, Sunghoon Park, Su Hwan Lee, Onyu Park, Tae Hwa Kim, Woo Hyun Cho
Received July 23, 2024   Accepted January 2, 2025   Published online January 6, 2025   
DOI: https://doi.org/10.4046/trd.2024.0109    [Epub ahead of print]
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Understanding of Patients with Severe COVID-19 Using Lung Ultrasound
Seo-Hee Yang, Eun Ju Park, Jung-Hyun Kim, Jin Woo Song, Young-Jae Cho
Received March 12, 2024   Accepted January 2, 2025   Published online January 6, 2025   
DOI: https://doi.org/10.4046/trd.2024.0025    [Epub ahead of print]
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Clinical significance of various pathogens identified in patients experiencing acute exacerbations of COPD: a multi-center study in South Korea
Hyun Woo Ji, Soojoung Yu, Yun Su Sim, Hyewon Seo, Jeong-Woong Park, Kyung Hoon Min, Deog Kyeom Kim, Hyun Woo Lee, Chin Kook Rhee, Yong Bum Park, Kyeong-Cheol Shin, Kwang Ha Yoo, Ji Ye Jung
Received July 4, 2024   Accepted December 16, 2024   Published online December 30, 2024   
DOI: https://doi.org/10.4046/trd.2024.0089    [Epub ahead of print]
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Reviews
Application of Artificial Intelligence in Thoracic Radiology: A Narrative Review
Woo Hyeon Lim, Hyungjin Kim
Received May 2, 2024   Accepted December 11, 2024   Published online December 17, 2024   
DOI: https://doi.org/10.4046/trd.2024.0062    [Epub ahead of print]
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Update in Association between Lung Cancer and Air Pollution
Jiye Yoo, Yongchan Lee, Youngil Park, Jongin Lee, Joon Young Choi, Heekwan Lee, Jeong Uk Lim
Received June 28, 2024   Accepted December 9, 2024   Published online December 11, 2024   
DOI: https://doi.org/10.4046/trd.2024.0092    [Epub ahead of print]
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Original Articles
Prevalence of New Frailty at Hospital Discharge in Severe COVID-19 Survivors and Its Associated Factors
Jong Hwan Jeong, Manbong Heo, Sunghoon Park, Su Hwan Lee, Onyu Park, Taehwa Kim, Hye Ju Yeo, Jin Ho Jang, Woo Hyun Cho, Jung-Wan Yoo
Received October 17, 2024   Accepted November 27, 2024   Published online December 5, 2024   
DOI: https://doi.org/10.4046/trd.2024.0160    [Epub ahead of print]
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Letters to the Editor
Request for Study Design Modification in Examining Nutritional Intake and Muscle Strength in Individuals with Airflow Limitation
Ming-Che Chang, Chii-Lan Lin, Fong-Fong Tsai, Hwei-Mei Tai, Chih-Wei Kuo, Hon-Kwong Ma, Chih-Chung Shiao
Received November 8, 2024   Accepted November 19, 2024   Published online November 25, 2024   
DOI: https://doi.org/10.4046/trd.2024.0171    [Epub ahead of print]
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Original Articles
Features of Lung Cyst in Birt-Hogg-Dubé Syndrome from Patients with Multiple Lung Cysts
Yong Jun Choi, Hye Jung Park, Chi Young Kim, Bo Mi Jung, Jae Hwa Cho, Min Kwang Byun
Received April 1, 2024   Accepted November 19, 2024   Published online November 25, 2024   
DOI: https://doi.org/10.4046/trd.2024.0045    [Epub ahead of print]
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Tuberculosis and
Respiratory Diseases

Print ISSN: 1738-3536
Online ISSN: 2005-6184

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