A Case of Congenital Cystic Adenomatoid Malformation of the Lng with Atypical Adenomatous Hyperplasia in Adult.

Lee, Ho Sung; Choi, Jae Sung; Seo, Ki Hyun; Na, Ju Ock; Kim, Yong Hoon; Oh, Mi Hye; Jou, Sung Shick

doi:2009.66.5.385

Tuberc Respir Dis > Volume 66(5); 2009 > Article

Case Report

Tuberculosis and Respiratory Diseases 2009;66(5):385-389.
DOI: https://doi.org/10.4046/trd.2009.66.5.385 Published online May 1, 2009.

A Case of Congenital Cystic Adenomatoid Malformation of the Lng with Atypical Adenomatous Hyperplasia in Adult.

Ho Sung Lee, Jae Sung Choi, Ki Hyun Seo, Ju Ock Na, Yong Hoon Kim, Mi Hye Oh, Sung Shick Jou

¹Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, College of Medicine, Cheonan, Korea. khseo@schca.ac.kr
²Department of Diagnostic Pathology, Soonchunhyang University Cheonan Hospital, College of Medicine, Cheonan, Korea.
³Department of Radiology, Soonchunhyang University Cheonan Hospital, College of Medicine, Cheonan, Korea.

Abstract

Congenital cystic adenomatoid malformation (CCAM), which is classified into five types according to size and bronchial invasion, is a rare type of developmental anomaly of the lung. CCAM is occasionally accompanied by malignancy, such as bronchioloalveolar carcinoma (BAC) or rhabdomyosarcoma. As defined by the WHO, atypical adenomatous hyperplasia (AAH) is a non-invasive spread of atypical epithelial cells in single rows along the alveolar wall, within a lesion that is usually less than 5 mm in diameter. AAH was also regarded as a pre-invasive neoplasia, especially associated with BAC and adenocarcinoma. We report a case of type II CCAM with AAH in adults, with a review of the references.

Key Words: Cystic adenomatoid malformation of lung, Congenital