Two cases of pulmonary eosinophilic granuloma.

Choi, Wan Young; Yoo, Yong Keol; Park, Dong Il; Shin, Dong Ho; Park, Sung Soo; Lee, Jung Hee; Jeon, Seok Chul; Chung, Won Sang; Park, Chan Pil; Park, Moon Hyang; Lee, Jung Dal

doi:1992.39.2.186

Tuberc Respir Dis > Volume 39(2); 1992 > Article

Original Article

Tuberculosis and Respiratory Diseases 1992;39(2):186-193.
DOI: https://doi.org/10.4046/trd.1992.39.2.186 Published online April 1, 1992.

Two cases of pulmonary eosinophilic granuloma.

Wan Young Choi¹, Yong Keol Yoo¹, Dong Il Park¹, Dong Ho Shin¹, Sung Soo Park¹, Jung Hee Lee¹, Seok Chul Jeon², Won Sang Chung³, Chan Pil Park⁴, Moon Hyang Park⁴, Jung Dal Lee⁴

¹Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea
²Department of Radiology, College of Medicine, Hanyang University, Seoul, Korea
³Department of Thoracic Surgery, College of Medicine, Hanyang University, Seoul, Korea
⁴Department of Pathoiogy, College of Medicine, Hanyang University, Seoul, Korea

Abstract

Eosinophilic granuloma (histiocytosis x) is an uncommon granulomatous disorder affecting the mononuclear phagocytic cell system caused by unknown etiology. When confined to the lungs, it is also known as pulmonary eosinophilic granuloma or pulmonary histiocytosis x. After the first case was described in 1951 by Farinacci et al, more 250 cases were reported in the English literature. However, only 4 cases has been introduced in our countη We describe two additional cases. In both cases, open lung biopsies are performed for definite diagnosis and examined by immunohistochemical stain for S-100 protein and electron microscopy for ultrastructural identification of Birbeck granule.

Key Words: Eosinophilic granuloma, Lung