Ventilatory dynamics in bronchiectasis. |
Yeon Jae Kim, Jae Yong Park, Tae Hoon Jung |
Department of Internal Medicine, School of Medicine, Kyungpook National University, Taegu, Korea |
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Abstract |
Background Bronchiectasis is a irreversible disease, a lot of cases of which are associated with chronic bronchitis, pulmonary emphysema and bronchial asthma due to chronic recurrent pulmonary infection. Therefore, pulmonary functions in bronchiectasis may also vary with associated diseases or involved segments.
Methods For the evaluation of ventilatory dynamics in bronchiectasis with respect to the pathoanatomic types of bronchiectasis and the degree of dyspnea, a total of 93 cases comprising 45 cases of tubular, 30 saccular and 18 mixed type of bronchiectasis whose clinical diagnosis was confirmed by bronchography were analyzed retrospectively. They were also divided into two groups: those with Hugh.Jones dyspnea grade 1 & 2 (group 1) and those with Hugh-Jones dyspnea grade 3 & 4 (group 11). Pulmonary functions tested in this study were analyses of cuπes of forced expiratory volume and flow-volume, and determinations of maximal voluntary ventilation and closing volumes.
Results The results were as follows;
1) The vital capacity and parameters reflecting expiratory flow rate except PEF were significantly reduced in saccular and mixed type than that in tubular type of bronchiectasis.
2) In saccular and mixed type, the maximal voluntary ventilation tended to decrease while CV / VC tended to increase.
3) As the degree of dyspnea became serious, the involved segments were progressively increased.
In contrast, ventilatory functions were significantly reduced in proportion to the severity of dyspnea.
Conclusion These findings suggest that in bronchiectasis, there be obstructive ventilatory impairment combined with mild restrictive ventilatory impairment, which becomes more prominent in saccular and mixed type and also as the degree of dyspnea progresses. |
Key Words:
Bronchiectasis, Ventilatory dynamics |
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