A Case with Mixed Infection of Actinomyces and Aspergillus in the Lung.

Lee, Suk Sue; Yang, Sei Hoon; Kim, Dong Kwan; Jang, Jae Jeong; Kim, Dong Soon

doi:1998.45.4.870

Tuberc Respir Dis > Volume 45(4); 1998 > Article

Case Report

Tuberculosis and Respiratory Diseases 1998;45(4):870-875.
DOI: https://doi.org/10.4046/trd.1998.45.4.870 Published online August 1, 1998.

A Case with Mixed Infection of Actinomyces and Aspergillus in the Lung.

Suk Sue Lee, Sei Hoon Yang, Dong Kwan Kim, Jae Jeong Jang, Dong Soon Kim

¹Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
²Department of Chest Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
³Department of Diagnostic Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Actinomycosis is a bacterial infection that can affect virtually any site in the body. There are three major forms of actinomycosis: cervicofacial, abdominal and thoracic. Aspergillus spp. are ubiquitous in the environment in most countries of the world. Pulmonary aspergillosis is clinically classified by aspergilloma, allergic bronchopulmonary aspergillosis and invasive aspergillosis. Actinomyces and Aspergillus, each of them was often reported in case, but mixed infection of both organisms have not kern reported. We experienced a case of mixed infection of Actinomyces and Aspergillus involving the same area of the lung in a 62 year-old housewife presented with hemoptysis and solitary pulmonary nodule. Percutaneous needle aspiration and later surgical resection revealed sulfur granule mixed with Aspergillus hyphae in the same lesion. We report this case with a review of the literature.

Key Words: Actinomycosis, Aspergillosis, Solitary pulmonary nodule