Successful Pulmonary Resection Combined with Chemotherapy for the Treatment of Mycobacterium avium Pulmonary Disease: A Case Report.

Koh, Won Jung; Kwon, O Jung; Kang, Eun Hae; Suh, Gee Young; Chung, Man Pyo; Kim, Hojoong; Kim, Kwhanmien; Lee, Nam Yong; Han, Joungho; Kim, Tae Sung; Lee, Kyung Soo

doi:2003.54.6.621

Tuberc Respir Dis > Volume 54(6); 2003 > Article

Case Report

Tuberculosis and Respiratory Diseases 2003;54(6):621-627.
DOI: https://doi.org/10.4046/trd.2003.54.6.621 Published online June 1, 2003.

Successful Pulmonary Resection Combined with Chemotherapy for the Treatment of Mycobacterium avium Pulmonary Disease: A Case Report.

Won Jung Koh, O Jung Kwon, Eun Hae Kang, Gee Young Suh, Man Pyo Chung, Hojoong Kim, Kwhanmien Kim, Nam Yong Lee, Joungho Han, Tae Sung Kim, Kyung Soo Lee

¹Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ojkwon@smc.samsung.co.kr
²Department of Thoracic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
³Department of Laboratory Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
⁴Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
⁵Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

The Mycobacterium avium complex (MAC) is the most common pathogen causing nontuberculous mycobacterial pulmonary disease. Despite the introduction of newer, more effective agents for the treatment of MAC, such as clarithromycin, the response to drug therapy in MAC pulmonary disease remains poor, and often frustrating. When MAC pulmonary disease has not been successfully eradicated using drug treatment alone, surgical management is still recognized to play a significant role. A case of MAC pulmonary disease, in a patient whose MAC disease was successfully treated by pulmonary resection, following the failure of drug therapy containing clarithromycin, is reported. To our knowledge, this is the first case report in Korea that the patient underwent a pulmonary resection for the treatment of MAC pulmonary disease.

Key Words: Atypical mycobacteria, Mycobacterium avium complex, Lung diseases, Thoracic surgery, Korea