A Case of Acromegaly Associated with Lung and Gastric Cancer.

Kim, Jin Soo; Kil, Uk Hyun; Song, Do Seon; Yang, Hong Jun; Lee, Hyeug; Huh, Min; Kim, Jeong Pyo; Kwon, Soon Seog; Kim, Young Kyoon; Kim, Kwan Hyoung; Moon, Hwa Sik; Song, Jeong Sup; Park, Sung Hak; Ahn, Joong Hyun

doi:2005.59.2.198

Tuberc Respir Dis > Volume 59(2); 2005 > Article

Case Report

Tuberculosis and Respiratory Diseases 2005;59(2):198-203.
DOI: https://doi.org/10.4046/trd.2005.59.2.198 Published online August 1, 2005.

A Case of Acromegaly Associated with Lung and Gastric Cancer.

Jin Soo Kim, Uk Hyun Kil, Do Seon Song, Hong Jun Yang, Hyeug Lee, Min Huh, Jeong Pyo Kim, Soon Seog Kwon, Young Kyoon Kim, Kwan Hyoung Kim, Hwa Sik Moon, Jeong Sup Song, Sung Hak Park, Joong Hyun Ahn

Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. ajhcmcim@olmh.co.kr

Abstract

Patients with acromegaly have high incidence of benign or malignant neoplasia than general population. Around fifteen percent of the deaths reported in acromegaly are attributable to malignancy of cancer. On the whole, mortality in acromegaly has been shown to be correlated with the degree of growth hormone (GH) control. Especially, the levels of insulin like growth factor-1 (IGF-1) may be higher in neoplasm, but there is no clear evidence to prove that tumor development is triggered by IGF-1 in acromegaly. Henceforth, we report a case of acromegaly associated with lung and gastric cancer in a 58-year-old man, suggesting the possible carcinogenic role of IGF-1.

Key Words: Acromegaly, Lung cancer, Gastric cancer