Two Cases of Bronchiolitis Obliterans Organizing Pneumonia treated with Steroid and Cyclosporine therapy.

Lee, Jong Hoo; Park, Myung Jae; Kim, Yi Hyung; Park, Byung Jo; Oh, Won Taek; Lee, Myung Yeol; Kang, Hong Mo; Yoo, Jee Hong

doi:2005.59.3.315

Tuberc Respir Dis > Volume 59(3); 2005 > Article

Case Report

Tuberculosis and Respiratory Diseases 2005;59(3):315-320.
DOI: https://doi.org/10.4046/trd.2005.59.3.315 Published online September 1, 2005.

Two Cases of Bronchiolitis Obliterans Organizing Pneumonia treated with Steroid and Cyclosporine therapy.

Jong Hoo Lee, Myung Jae Park, Yi Hyung Kim, Byung Jo Park, Won Taek Oh, Myung Yeol Lee, Hong Mo Kang, Jee Hong Yoo

Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea. sekyukim@yumc.yonsei.ac.kr

Abstract

A rapid response to corticosteroid treatment and a generally favourable outcome are characteristic features of BOOP (Bronchiolitis obliterans organizing pneumonia). However, with increasing experience of the clinical spectrum of this disease, it is now recognized that some patients are refractory to steroid, which is associated with a poor prognosis. Here, two cases of BOOP initially treated with predinisone and antibiotics without effects, but subsequently responded to secondary cyclosporine treatment, are reported.

Key Words: Cyclosporine, BOOP (Bronchiolitis Obliterans Organizing Pneumonia)