A Case of Cancer Associated Retinopathy with Small Cell Lung Carcinoma.

Lim, Seongmin; Bae, Jongoh; Cho, Sanggeon; Kang, Sanggu; Lee, Eunyoung; Kim, Sungkuk; Kim, Young; Kwak, Jinyoung; Kim, Kwiwan

doi:2005.59.6.679

Tuberc Respir Dis > Volume 59(6); 2005 > Article

Case Report

Tuberculosis and Respiratory Diseases 2005;59(6):679-683.
DOI: https://doi.org/10.4046/trd.2005.59.6.679 Published online December 1, 2005.

A Case of Cancer Associated Retinopathy with Small Cell Lung Carcinoma.

Seongmin Lim, Jongoh Bae, Sanggeon Cho, Sanggu Kang, Eunyoung Lee, Sungkuk Kim, Young Kim, Jinyoung Kwak, Kwiwan Kim

¹Department of Internal medicine, Presbyterian Medical Center, Jeonju, Korea. drnbear@gmail.com
²Department of Internal medicine, Chonbuk National University Medical School, Korea.
³Kim kwiwan Medical Clinic, Jeonju, Korea.

Abstract

Cancer associated retinopathy (CAR) syndrome is a very rare ocular manifestation of paraneoplastic syndrome, and is characterized clinically by progressive visual impairment. Immune cross-reactivity between antigens in the cancerous tissue and antigens in the retina may play an important role in its pathogenesis, and most of cases are associated with lung carcinoma, particularly small cell lung cancer. The clinical triad of CAR is described as photosensitivity, ring scotomata, and an attenuated retinal arterial caliber. Here, we report a 61-year old male patient with CAR syndrome, who had small cell lung carcinoma in the stage of limited disease, with a brief review of the relevant literature.

Key Words: Cancer associated retinopathy, CAR syndrome, Paraneoplastic syndrome, Small cell lung cancer