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Endometrial Stromal Sarcoma Presented as an Incidental Lung Mass with Multiple Pulmonary Nodules
Dong Oh Kang, M.D.1, Sue In Choi, M.D.1, Jee Youn Oh, M.D.1, Jae Kyeom Sim, M.D.1, Jong Hyun Choi, M.D.1, Ji Yung Choo, M.D., Ph.D.2, Jin Wook Hwang, M.D., Ph.D.3, Seung Heon Lee, M.D., Ph.D.1, Ju-Han Lee, M.D., Ph.D.4, Ki Yeol Lee, M.D., Ph.D.2, Chol Shin, M.D., Ph.D.1 and Je Hyeong Kim, M.D., Ph.D.1
1Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine, Departments of 2Radiology, 3Thoracic and Cardiovascular Surgery, and 4Pathology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea
Tuberculosis and Respiratory Diseases; 2014 March; 76 (3): 131-135

FullText

Conclusion : Low-grade endometrial stromal sarcoma (ESS) is an uncommon gynecologic malignancy of mesodermal origin. Pulmonary metastasis of low-grade ESS can occur years and decades after the treatment of the primary disease. Low-grade ESS is frequently mistaken as benign uterine neoplasm like uterine leiomyoma, which can potentially lead to a misdiagnosis. We present a case of a 42-year-old woman with low-grade ESS, that initially presented as an incidental lung mass with multiple pulmonary nodules, seven years after an uterine myomectomy. A 6.9Ąż5.8 cm-sized intrapelvic mass suspected of uterine origin was discovered while searching for potential extrathoracic primary origin. A pelviscopy and simultaneous thoracoscopic lung biopsy were conducted for pathologic diagnosis. Finally, the diagnosis was confirmed as low-grade ESS with lung metastasis based on the histopathologic examination with immunohistochemical stain, which was showed positive for CD10 and hormone receptor markers (estrogen and progesterone receptors) in both pelvic and lung specimens.

Keywords : Sarcoma, Endometrial Stromal; Multiple Pulmonary Nodules; Neoplasm Metastasis

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